In my opinion, the biggest annoyance with insulin pumps is the sites and changing sites. It is substantially better with the OmniPod for insertion. However, the biggest problem has to do with pooling of insulin at the site. Basically, eat a big meal, and take a large bolus. The insulin has a tendancy to pool at the site. And if I decide to change my infusion set/pod a short time after taking this insulin — well, most of it is going to fall out.
Even though I give myself the correct dosing, if I decide to change my site after eating, I will go high unless I administer a guesstimate of how much insulin I have lost. A big part of the calculation has to do with how long after eating/how long after giving myself the bolus. Almost impossible to get right.
Moral of the story: never give yourself a bolus right before you change your set. It never works.
